In fall 2003, the Six Sigma-Concept for the small and medium business enterprises (SME) was designed within the context of this final thesis in Department T of the Zurich University of Applied Sciences Winterthur. Until now, Six Sigma projects were practically realized only in large companies. For SME firms, there has not existed any such ?recipe-book? so far. The employment of this concept is to help such a SME firm to introduce the Six Sigma method quickly and at low cost. The Six Sigma approach is an enterprise-wide initiative, which is based on the income statement and which aims at cost reduction and sales increase. The statistical process control represents the core of Six Sigma and is being converted into a formalised methodology. Through the application of the established means of statistics a mistake measure (FpMM = mistakes per million possibilities) for the efficiency of a process is defined. Using the right combination and matching of these statistical means this value can be decreased with little additional expenses. The aim of the Six Sigma application is the achievement of a zero-mistake organization. This organization works with processes which attain the 6-level. This corresponds to a mistake means of 3.4 FpMM. In the theoretical part, a wide knowledge about quality-ensuring methods and means is being procured. The concept is built on these grounds. It is enclosed in itself and can be employed as an accompanying document at the introduction of Six Sigma. Practical worked samples, which are based on statistics, make clear the possibilities which Six Sigma enables. Further, a true case, which could have certainly been avoided using Six Sigma, will be presented. A comparison with existing quality management initiatives depicts that Six Sigma comes very close to the procedures according to the optimisation paradigm. Therefore, it is very suitable as a basis for a total quality management system.